Publications

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A ChatGPT-4 representation of our publications

  1. Tian C, Bürki C, Westerman KE, Patel CJ. Association between timing and consistency of physical activity and type 2 diabetes: a cohort study on participants of the UK Biobank. Diabetologia. 2023 Sep 20. PMID: 37728730

  2. Fard P, Chung MKJ, Estiri H, Patel CJ. Spatio-temporal interpolation and delineation of extreme heat events in California between 2017 and 2021. Environ Res. 2023 Aug 28; 237(Pt 2):116984. PMID: 37648196

  3. Gregg EW, Patorno E, Karter AJ, Mehta R, Huang ES, White M, Patel CJ, McElvaine AT, Cefalu WT, Selby J, Riddle MC, Khunti K. Use of Real-World Data in Population Science to Improve the Prevention and Care of Diabetes-Related Outcomes. Diabetes Care. 2023 07 01; 46(7):1316-1326. PMID: 37339346; PMCID: PMC10300521

  4. Chung MK, Caboni M, Strandwitz P, D’Onofrio A, Lewis K, Patel CJ. Corrigendum to “Systematic comparisons between Lyme disease and post-treatment Lyme disease syndrome in the U.S. with administrative claims data”. EBioMedicine. 2023 Jul; 93:104652. PMID: 37343362; PMCID: PMC10363426

  5. Estiri H, Azhir A, Blacker DL, Ritchie CS, Patel CJ, Murphy SN. Temporal characterization of Alzheimer’s Disease with sequences of clinical records. EBioMedicine. 2023 Jun; 92:104629. PMID: 37247495; PMCID: PMC10236187

  6. Axfors C, Patel CJ, Ioannidis JPA. Published registry-based pharmacoepidemiologic associations show limited concordance with agnostic medication-wide analyses. J Clin Epidemiol. 2023 08; 160:33-45. PMID: 37224981

  7. Cromer SJ, Lakhani CM, Mercader JM, Majarian TD, Schroeder P, Cole JB, Florez JC, Patel CJ, Manning AK, Burnett-Bowie SM, Merino J, Udler MS. Association and Interaction of Genetics and Area-Level Socioeconomic Factors on the Prevalence of Type 2 Diabetes and Obesity. Diabetes Care. 2023 05 01; 46(5):944-952. PMID: 36787958; PMCID: PMC10154653

  8. Andrews B, Wongchokprasitti C, Visweswaran S, Lakhani CM, Patel CJ, Cooper GF. A new method for estimating the probability of causal relationships from observational data: Application to the study of the short-term effects of air pollution on cardiovascular and respiratory disease. Artif Intell Med. 2023 05; 139:102546. PMID: 37100513; PMCID: PMC10171833

  9. Zimmerman S, Tierney BT, Patel CJ, Kostic AD. Quantifying Shared and Unique Gene Content across 17 Microbial Ecosystems. mSystems. 2023 04 27; 8(2):e0011823. PMID: 37022232; PMCID: PMC10134805

  10. He Y, Qian DC, Diao JA, Cho MH, Silverman EK, Gusev A, Manrai AK, Martin AR, Patel CJ. Prediction and stratification of longitudinal risk for chronic obstructive pulmonary disease across smoking behaviors. medRxiv. 2023 Apr 05. PMID: 37066248; PMCID: PMC10104210

  11. Tangirala S, Tierney BT, Patel CJ. Prioritization of COVID-19 risk factors in July 2020 and February 2021 in the UK. Commun Med (Lond). 2023 Mar 30; 3(1):45. PMID: 36997659; PMCID: PMC10062272

  12. Chung MK, Caboni M, Strandwitz P, D’Onofrio A, Lewis K, Patel CJ. Systematic comparisons between Lyme disease and post-treatment Lyme disease syndrome in the U.S. with administrative claims data. EBioMedicine. 2023 Apr; 90:104524. PMID: 36958992; PMCID: PMC10114153

  13. Nguyen VK, Middleton LYM, Huang L, Zhao N, Verly E, Kvasnicka J, Sagers L, Patel CJ, Colacino J, Jolliet O. Harmonized US National Health and Nutrition Examination Survey 1988-2018 for high throughput exposome-health discovery. medRxiv. 2023 Feb 08. PMID: 36798185; PMCID: PMC9934713

  14. Le Goallec A, Collin S, Jabri M, Diai S, Vincent T, Patel CJ. Machine learning approaches to predict age from accelerometer records of physical activity at biobank scale. PLOS Digit Health. 2023 Jan; 2(1):e0000176. PMID: 36812610; PMCID: PMC9931315

  15. Islam MZ, Tran M, Xu T, Tierney BT, Patel C, Kostic AD. Reproducible and opposing gut microbiome signatures distinguish autoimmune diseases and cancers: a systematic review and meta-analysis. Microbiome. 2022 12 09; 10(1):218. PMID: 36482486; PMCID: PMC9733034

  16. Rasooly D, Yang Q, Moonesinghe R, Khoury MJ, Patel CJ. The Joint Public Health Impact of Family History of Diabetes and Cardiovascular Disease among Adults in the United States: A Population-Based Study. Public Health Genomics. 2022 Oct 06; 1-12. PMID: 36202082; PMCID: PMC10076442

  17. Zeraatkar D, Pitre T, Leung G, Cusano E, Agarwal A, Khalid F, Escamilla Z, Cooper MA, Ghadimi M, Wang Y, Verdugo-Paiva F, Rada G, Kum E, Qasim A, Bartoszko JJ, Siemieniuk RAC, Patel C, Guyatt G, Brignardello-Petersen R. Consistency of covid-19 trial preprints with published reports and impact for decision making: retrospective review. BMJ Med. 2022; 1(1):e000309. PMID: 36936583; PMCID: PMC9951374

  18. Claypool K, Long MT, Patel CJ. Reply. Clin Gastroenterol Hepatol. 2023 Jun; 21(6):1672-1673. PMID: 36087712

  19. Patel CJ, Claypool KT, Chow E, Chung MK, Mai D, Chen J, Bendavid E. The demographic and socioeconomic correlates of behavior and HIV infection status across sub-Saharan Africa. Commun Med (Lond). 2022; 2:104. PMID: 35992892; PMCID: PMC9388647

  20. Choi KW, Wilson M, Ge T, Kandola A, Patel CJ, Lee SH, Smoller JW. Integrative analysis of genomic and exposomic influences on youth mental health. J Child Psychol Psychiatry. 2022 10; 63(10):1196-1205. PMID: 35946823

  21. Nguyen VK, Colacino J, Patel CJ, Sartor M, Jolliet O. Identification of occupations susceptible to high exposure and risk associated with multiple toxicants in an observational study: National Health and Nutrition Examination Survey 1999-2014. Exposome. 2022; 2(1):osac004. PMID: 35832257; PMCID: PMC9266352

  22. Boorgu DSSK, Venkatesh S, Lakhani CM, Walker E, Aguerre IM, Riley C, Patel CJ, De Jager PL, Xia Z. The impact of socioeconomic status on subsequent neurological outcomes in multiple sclerosis. Mult Scler Relat Disord. 2022 Sep; 65:103994. PMID: 35780727; PMCID: PMC9444968

  23. Claypool K, Long MT, Patel CJ. Waist Circumference and Insulin Resistance Are the Most Predictive Metabolic Factors for Steatosis and Fibrosis. Clin Gastroenterol Hepatol. 2023 Jul; 21(7):1950-1954.e1. PMID: 35671890; PMCID: PMC9722977

  24. Le Goallec A, Diai S, Collin S, Prost JB, Vincent T, Patel CJ. Using deep learning to predict abdominal age from liver and pancreas magnetic resonance images. Nat Commun. 2022 04 13; 13(1):1979. PMID: 35418184; PMCID: PMC9007982

  25. He Y, Patel CJ. Shared exposure liability of type 2 diabetes and other chronic conditions in the UK Biobank. Acta Diabetol. 2022 Jun; 59(6):851-860. PMID: 35348899; PMCID: PMC9085680

  26. Siontis GC, Bhatt DL, Patel CJ. Secular Trends in Prevalence of Heart Failure Diagnosis over 20 Years (from the US NHANES). Am J Cardiol. 2022 06 01; 172:161-164. PMID: 35361480; PMCID: PMC9277570

  27. Tierney BT, Tan Y, Yang Z, Shui B, Walker MJ, Kent BM, Kostic AD, Patel CJ. Systematically assessing microbiome-disease associations identifies drivers of inconsistency in metagenomic research. PLoS Biol. 2022 03; 20(3):e3001556. PMID: 35235560; PMCID: PMC8890741

  28. Siontis GCM, Sweda R, Noseworthy PA, Friedman PA, Siontis KC, Patel CJ. Development and validation pathways of artificial intelligence tools evaluated in randomised clinical trials. BMJ Health Care Inform. 2021 Dec; 28(1). PMID: 34969668; PMCID: PMC8718483

  29. Walker DI, Hart JE, Patel CJ, Rudel R, Chu JH, Garshick E, Pennell KD, Laden F, Jones DP. Integrated molecular response of exposure to traffic-related pollutants in the US trucking industry. Environ Int. 2022 01; 158:106957. PMID: 34737152; PMCID: PMC9624233

  30. Tierney BT, Szymanski E, Henriksen JR, Kostic AD, Patel CJ. Using Cartesian Doubt To Build a Sequencing-Based View of Microbiology. mSystems. 2021 Oct 26; 6(5):e0057421. PMID: 34636670; PMCID: PMC8510522

  31. Chung MK, Smith MR, Lin Y, Walker DI, Jones D, Patel CJ, Kong SW. Plasma metabolomics of autism spectrum disorder and influence of shared components in proband families. Exposome. 2021; 1(1):osab004. PMID: 35028569; PMCID: PMC8739333

  32. Estiri H, Strasser ZH, Brat GA, Semenov YR, Patel CJ, Murphy SN. Evolving phenotypes of non-hospitalized patients that indicate long COVID. BMC Med. 2021 09 27; 19(1):249. PMID: 34565368; PMCID: PMC8474909

  33. Velaer K, Thomas IC, Yang J, Kapphahn K, Metzner TJ, Golla A, Hoerner CR, Fan AC, Master V, Chertow GM, Brooks JD, Patel CJ, Desai M, Leppert JT. Clinical laboratory tests associated with survival in patients with metastatic renal cell carcinoma: A Laboratory Wide Association Study (LWAS). Urol Oncol. 2022 01; 40(1):12.e23-12.e30. PMID: 34580027; PMCID: PMC10313329

  34. Tierney BT, Anderson E, Tan Y, Claypool K, Tangirala S, Kostic AD, Manrai AK, Patel CJ. Leveraging vibration of effects analysis for robust discovery in observational biomedical data science. PLoS Biol. 2021 09; 19(9):e3001398. PMID: 34555021; PMCID: PMC8510627

  35. Nguyen VK, Colacino J, Chung MK, Goallec AL, Jolliet O, Patel CJ. Characterising the relationships between physiological indicators and all-cause mortality (NHANES): a population-based cohort study. Lancet Healthy Longev. 2021 10; 2(10):e651-e662. PMID: 34825242; PMCID: PMC8612451

  36. Chung MK, Rappaport SM, Wheelock CE, Nguyen VK, van der Meer TP, Miller GW, Vermeulen R, Patel CJ. Utilizing a Biology-Driven Approach to Map the Exposome in Health and Disease: An Essential Investment to Drive the Next Generation of Environmental Discovery. Environ Health Perspect. 2021 08; 129(8):85001. PMID: 34435882; PMCID: PMC8388254

  37. Nichol AA, Bendavid E, Mutenherwa F, Patel C, Cho MK. Diverse experts’ perspectives on ethical issues of using machine learning to predict HIV/AIDS risk in sub-Saharan Africa: a modified Delphi study. BMJ Open. 2021 07 28; 11(7):e052287. PMID: 34321310; PMCID: PMC8320245

  38. Estiri H, Strasser ZH, Brat GA, Semenov YR, Patel CJ, Murphy SN. Evolving Phenotypes of non-hospitalized Patients that Indicate Long Covid. medRxiv. 2021 Jul 10. PMID: 33948602; PMCID: PMC8095212

  39. Tierney BT, Tan Y, Kostic AD, Patel CJ. Gene-level metagenomic architectures across diseases yield high-resolution microbiome diagnostic indicators. Nat Commun. 2021 05 18; 12(1):2907. PMID: 34006865; PMCID: PMC8131609

  40. Claypool K, Patel CJ. Prevalence of Fatty Liver Disease is Driven by Prediabetes and Diabetes: US NHANES 2017-2018. Clin Gastroenterol Hepatol. 2022 03; 20(3):712-713. PMID: 33965575; PMCID: PMC10291529

  41. van der Meer TP, Wolffenbuttel BHR, Patel CJ. Data-driven assessment, contextualisation and implementation of 134 variables in the risk for type 2 diabetes: an analysis of Lifelines, a prospective cohort study in the Netherlands. Diabetologia. 2021 06; 64(6):1268-1278. PMID: 33710397; PMCID: PMC8099846

  42. Klau S, Hoffmann S, Patel CJ, Ioannidis JP, Boulesteix AL. Examining the robustness of observational associations to model, measurement and sampling uncertainty with the vibration of effects framework. Int J Epidemiol. 2021 03 03; 50(1):266-278. PMID: 33147614; PMCID: PMC7938511

  43. Pho N, Manrai AK, Leppert JT, Chertow GM, Ioannidis JPA, Patel CJ. Association of 152 Biomarker Reference Intervals with All-Cause Mortality in Participants of a General United States Survey from 1999 to 2010. Clin Chem. 2021 03 01; 67(3):500-507. PMID: 33674838

  44. van der Meer TP, Chung MK, van Faassen M, Makris KC, van Beek AP, Kema IP, Wolffenbuttel BHR, van Vliet-Ostaptchouk JV, Patel CJ. Temporal exposure and consistency of endocrine disrupting chemicals in a longitudinal study of individuals with impaired fasting glucose. Environ Res. 2021 06; 197:110901. PMID: 33617867; PMCID: PMC9162187

  45. He Y, Lakhani CM, Rasooly D, Manrai AK, Tzoulaki I, Patel CJ. Comparisons of Polyexposure, Polygenic, and Clinical Risk Scores in Risk Prediction of Type 2 Diabetes. Diabetes Care. 2021 04; 44(4):935-943. PMID: 33563654; PMCID: PMC7985424

  46. Passero K, Setia-Verma S, McAllister K, Manrai A, Patel C, Hall M. What about the environment? Leveraging multi-omic datasets to characterize the environment’s role in human health. Pac Symp Biocomput. 2021; 26:309-315. PMID: 34409132; PMCID: PMC8323787

  47. Passero K, Setia-Verma S, McAllister K, Manrai A, Patel C, Hall M. What about the environment? Leveraging multi-omic datasets to characterize the environment’s role in human health. Pac Symp Biocomput. 2021; 26:309-315. PMID: 33691027

  48. Sohlberg EM, Thomas IC, Yang J, Kapphahn K, Velaer KN, Goldstein MK, Wagner TH, Chertow GM, Brooks JD, Patel CJ, Desai M, Leppert JT. Laboratory-wide association study of survival with prostate cancer. Cancer. 2021 04 01; 127(7):1102-1113. PMID: 33237577; PMCID: PMC10245385

  49. Cromer SJ, Lakhani CM, Wexler DJ, Burnett-Bowie SM, Udler M, Patel CJ. Geospatial Analysis of Individual and Community-Level Socioeconomic Factors Impacting SARS-CoV-2 Prevalence and Outcomes. medRxiv. 2020 Sep 30. PMID: 33024982; PMCID: PMC7536884

  50. Krissaane I, De Niz C, Gutiérrez-Sacristán A, Korodi G, Ede N, Kumar R, Lyons J, Manrai A, Patel C, Kohane I, Avillach P. Scalability and cost-effectiveness analysis of whole genome-wide association studies on Google Cloud Platform and Amazon Web Services. J Am Med Inform Assoc. 2020 09 01; 27(9):1425-1430. PMID: 32719837; PMCID: PMC7534581

  51. Alfano R, Chadeau-Hyam M, Ghantous A, Keski-Rahkonen P, Chatzi L, Perez AE, Herceg Z, Kogevinas M, de Kok TM, Nawrot TS, Novoloaca A, Patel CJ, Pizzi C, Robinot N, Rusconi F, Scalbert A, Sunyer J, Vermeulen R, Vrijheid M, Vineis P, Robinson O, Plusquin M. A multi-omic analysis of birthweight in newborn cord blood reveals new underlying mechanisms related to cholesterol metabolism. Metabolism. 2020 09; 110:154292. PMID: 32553738; PMCID: PMC7450273

  52. Elhadad MA, Karavasiloglou N, Wulaningsih W, Tsilidis KK, Tzoulaki I, Patel CJ, Rohrmann S. Metabolites, Nutrients, and Lifestyle Factors in Relation to Coffee Consumption: An Environment-Wide Association Study. Nutrients. 2020 May 19; 12(5). PMID: 32438643; PMCID: PMC7284649

  53. Le Goallec A, Tierney BT, Luber JM, Cofer EM, Kostic AD, Patel CJ. A systematic machine learning and data type comparison yields metagenomic predictors of infant age, sex, breastfeeding, antibiotic usage, country of origin, and delivery type. PLoS Comput Biol. 2020 05; 16(5):e1007895. PMID: 32392251

  54. Sagers L, Melas-Kyriazi L, Patel CJ, Manrai AK. Prediction of chronological and biological age from laboratory data. Aging (Albany NY). 2020 05 05; 12(9):7626-7638. PMID: 32391803; PMCID: PMC7244024

  55. Claypool KT, Chung MK, Deonarine A, Gregg EW, Patel CJ. Characteristics of undiagnosed diabetes in men and women under the age of 50 years in the Indian subcontinent: the National Family Health Survey (NFHS-4)/Demographic Health Survey 2015-2016. BMJ Open Diabetes Res Care. 2020 02; 8(1). PMID: 32098896; PMCID: PMC7206915

  56. Papadimitriou N, Muller D, van den Brandt PA, Geybels M, Patel CJ, Gunter MJ, Lopez DS, Key TJ, Perez-Cornago A, Ferrari P, Vineis P, Weiderpass E, Boeing H, Agudo A, Sánchez MJ, Overvad K, Kühn T, Fortner RT, Palli D, Drake I, Bjartell A, Santiuste C, Bueno-de-Mesquita BH, Krogh V, Tjønneland A, Lauritzen DF, Gurrea AB, Quirós JR, Stattin P, Trichopoulou A, Martimianaki G, Karakatsani A, Thysell E, Johansson I, Ricceri F, Tumino R, Larrañaga N, Khaw KT, Riboli E, Tzoulaki I, Tsilidis KK. A nutrient-wide association study for risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition and the Netherlands Cohort Study. Eur J Nutr. 2020 Oct; 59(7):2929-2937. PMID: 31705265; PMCID: PMC7501135

  57. Johnston BC, Zeraatkar D, Han MA, Vernooij RWM, Valli C, El Dib R, Marshall C, Stover PJ, Fairweather-Taitt S, Wójcik G, Bhatia F, de Souza R, Brotons C, Meerpohl JJ, Patel CJ, Djulbegovic B, Alonso-Coello P, Bala MM, Guyatt GH. Unprocessed Red Meat and Processed Meat Consumption: Dietary Guideline Recommendations From the Nutritional Recommendations (NutriRECS) Consortium. Ann Intern Med. 2019 11 19; 171(10):756-764. PMID: 31569235

  58. Tierney BT, Yang Z, Luber JM, Beaudin M, Wibowo MC, Baek C, Mehlenbacher E, Patel CJ, Kostic AD. The Landscape of Genetic Content in the Gut and Oral Human Microbiome. Cell Host Microbe. 2019 08 14; 26(2):283-295.e8. PMID: 31415755; PMCID: PMC6716383

  59. Rasooly D, Ioannidis JPA, Khoury MJ, Patel CJ. Family History-Wide Association Study to Identify Clinical and Environmental Risk Factors for Common Chronic Diseases. Am J Epidemiol. 2019 08 01; 188(8):1563-1568. PMID: 31172187; PMCID: PMC6670049

  60. Manrai AK, Ioannidis JPA, Patel CJ. Signals Among Signals: Prioritizing Nongenetic Associations in Massive Data Sets. Am J Epidemiol. 2019 05 01; 188(5):846-850. PMID: 30877292; PMCID: PMC6494664

  61. Lakhani CM, Tierney BT, Manrai AK, Yang J, Visscher PM, Patel CJ. Author Correction: Repurposing large health insurance claims data to estimate genetic and environmental contributions in 560 phenotypes. Nat Genet. 2019 04; 51(4):764-765. PMID: 30814726

  62. Le Goallec A, Patel CJ. Age-dependent co-dependency structure of biomarkers in the general population of the United States. Aging (Albany NY). 2019 02 28; 11(5):1404-1426. PMID: 30822279; PMCID: PMC6428110

  63. Rasooly D, Patel CJ. Conducting a Reproducible Mendelian Randomization Analysis Using the R Analytic Statistical Environment. Curr Protoc Hum Genet. 2019 04; 101(1):e82. PMID: 30645041; PMCID: PMC6424604

  64. Lakhani CM, Tierney BT, Manrai AK, Yang J, Visscher PM, Patel CJ. Repurposing large health insurance claims data to estimate genetic and environmental contributions in 560 phenotypes. Nat Genet. 2019 02; 51(2):327-334. PMID: 30643253; PMCID: PMC6358510

  65. Chung MK, Buck Louis GM, Kannan K, Patel CJ. Exposome-wide association study of semen quality: Systematic discovery of endocrine disrupting chemical biomarkers in fertility require large sample sizes. Environ Int. 2019 04; 125:505-514. PMID: 30583854; PMCID: PMC6400484

  66. Sagers JE, Brown AS, Vasilijic S, Lewis RM, Sahin MI, Landegger LD, Perlis RH, Kohane IS, Welling DB, Patel CJ, Stankovic KM. Publisher Correction: Computational repositioning and preclinical validation of mifepristone for human vestibular schwannoma. Sci Rep. 2018 Nov 23; 8(1):17449. PMID: 30470790; PMCID: PMC6251932

  67. Wolthers BO, Frandsen TL, Patel CJ, Abaji R, Attarbaschi A, Barzilai S, Colombini A, Escherich G, Grosjean M, Krajinovic M, Larsen E, Liang DC, Möricke A, Rasmussen KK, Samarasinghe S, Silverman LB, van der Sluis IM, Stanulla M, Tulstrup M, Yadav R, Yang W, Zapotocka E, Gupta R, Schmiegelow K. Trypsin-encoding PRSS1-PRSS2 variations influence the risk of asparaginase-associated pancreatitis in children with acute lymphoblastic leukemia: a Ponte di Legno toxicity working group report. Haematologica. 2019 03; 104(3):556-563. PMID: 30467200; PMCID: PMC6395330

  68. Manrai AK, Patel CJ, Ioannidis JPA. Using Big Data to Determine Reference Values for Laboratory Tests-Reply. JAMA. 2018 10 09; 320(14):1496. PMID: 30304422; PMCID: PMC7257917

  69. Wijetunga I, Ecuyer C, Martinez-Lopez S, Jameel M, Baker RJ, Welberry Smith M, Patel C, Weston M, Ahmad N. Renal transplant from infant and neonatal donors is a feasible option for the treatment of end-stage renal disease but is associated with increased early graft loss. Am J Transplant. 2018 11; 18(11):2679-2688. PMID: 29981206

  70. Chung MK, Kannan K, Louis GM, Patel CJ. Toward Capturing the Exposome: Exposure Biomarker Variability and Coexposure Patterns in the Shared Environment. Environ Sci Technol. 2018 08 07; 52(15):8801-8810. PMID: 29972023; PMCID: PMC6085725

  71. Estiri H, Patel CJ, Murphy SN. Informatics can help providers incorporate context into care. JAMIA Open. 2018 Jul; 1(1):3-6. PMID: 31984312; PMCID: PMC6951901

  72. Corona E, Wang L, Ko D, Patel CJ. Systematic detection of positive selection in the human-pathogen interactome and lasting effects on infectious disease susceptibility. PLoS One. 2018; 13(5):e0196676. PMID: 29799843

  73. Manrai AK, Patel CJ, Ioannidis JPA. In the Era of Precision Medicine and Big Data, Who Is Normal? JAMA. 2018 May 15; 319(19):1981-1982. PMID: 29710130; PMCID: PMC7572221

  74. Luber JM, Tierney BT, Cofer EM, Patel CJ, Kostic AD. Aether: leveraging linear programming for optimal cloud computing in genomics. Bioinformatics. 2018 05 01; 34(9):1565-1567. PMID: 29228186

  75. Patel CJ, Bhattacharya J, Ioannidis JPA, Bendavid E. Systematic identification of correlates of HIV infection: an X-wide association study. AIDS. 2018 04 24; 32(7):933-943. PMID: 29424772; PMCID: PMC5869155

  76. Gutiérrez-Sacristán A, Guedj R, Korodi G, Stedman J, Furlong LI, Patel CJ, Kohane IS, Avillach P. Rcupcake: an R package for querying and analyzing biomedical data through the BD2K PIC-SURE RESTful API. Bioinformatics. 2018 04 15; 34(8):1431-1432. PMID: 29267850

  77. Sagers JE, Brown AS, Vasilijic S, Lewis RM, Sahin MI, Landegger LD, Perlis RH, Kohane IS, Welling DB, Patel CJ, Stankovic KM. Computational repositioning and preclinical validation of mifepristone for human vestibular schwannoma. Sci Rep. 2018 04 03; 8(1):5437. PMID: 29615643; PMCID: PMC5882888

  78. Wilson A, Zigler CM, Patel CJ, Dominici F. Model-averaged confounder adjustment for estimating multivariate exposure effects with linear regression. Biometrics. 2018 09; 74(3):1034-1044. PMID: 29569228; PMCID: PMC6518418

  79. Brown AS, Rasooly D, Patel CJ. Leveraging Population-Based Clinical Quantitative Phenotyping for Drug Repositioning. CPT Pharmacometrics Syst Pharmacol. 2018 02; 7(2):124-129. PMID: 28941007

  80. Tangirala S, Patel CJ. Integrated Analysis of Gene Expression Differences in Twins Discordant for Disease and Binary Phenotypes. Sci Rep. 2018 01 08; 8(1):17. PMID: 29311748

  81. Brown AS, Patel CJ. A review of validation strategies for computational drug repositioning. Brief Bioinform. 2018 01 01; 19(1):174-177. PMID: 27881429; PMCID: PMC5862266

  82. Johnson CH, Athersuch TJ, Collman GW, Dhungana S, Grant DF, Jones DP, Patel CJ, Vasiliou V. Yale school of public health symposium on lifetime exposures and human health: the exposome; summary and future reflections. Hum Genomics. 2017 Dec 08; 11(1):32. PMID: 29221465; PMCID: PMC5723043

  83. Aschard H, Guillemot V, Vilhjalmsson B, Patel CJ, Skurnik D, Ye CJ, Wolpin B, Kraft P, Zaitlen N. Covariate selection for association screening in multiphenotype genetic studies. Nat Genet. 2017 Dec; 49(12):1789-1795. PMID: 29038595; PMCID: PMC5797835

  84. Gauderman WJ, Mukherjee B, Aschard H, Hsu L, Lewinger JP, Patel CJ, Witte JS, Amos C, Tai CG, Conti D, Torgerson DG, Lee S, Chatterjee N. Update on the State of the Science for Analytical Methods for Gene-Environment Interactions. Am J Epidemiol. 2017 Oct 01; 186(7):762-770. PMID: 28978192; PMCID: PMC5859988

  85. McAllister K, Mechanic LE, Amos C, Aschard H, Blair IA, Chatterjee N, Conti D, Gauderman WJ, Hsu L, Hutter CM, Jankowska MM, Kerr J, Kraft P, Montgomery SB, Mukherjee B, Papanicolaou GJ, Patel CJ, Ritchie MD, Ritz BR, Thomas DC, Wei P, Witte JS. Current Challenges and New Opportunities for Gene-Environment Interaction Studies of Complex Diseases. Am J Epidemiol. 2017 Oct 01; 186(7):753-761. PMID: 28978193; PMCID: PMC5860428

  86. Patel CJ, Kerr J, Thomas DC, Mukherjee B, Ritz B, Chatterjee N, Jankowska M, Madan J, Karagas MR, McAllister KA, Mechanic LE, Fallin MD, Ladd-Acosta C, Blair IA, Teitelbaum SL, Amos CI. Opportunities and Challenges for Environmental Exposure Assessment in Population-Based Studies. Cancer Epidemiol Biomarkers Prev. 2017 09; 26(9):1370-1380. PMID: 28710076

  87. Magni P, Bier DM, Pecorelli S, Agostoni C, Astrup A, Brighenti F, Cook R, Folco E, Fontana L, Gibson RA, Guerra R, Guyatt GH, Ioannidis JP, Jackson AS, Klurfeld DM, Makrides M, Mathioudakis B, Monaco A, Patel CJ, Racagni G, Schünemann HJ, Shamir R, Zmora N, Peracino A. Perspective: Improving Nutritional Guidelines for Sustainable Health Policies: Current Status and Perspectives. Adv Nutr. 2017 Jul; 8(4):532-545. PMID: 28710141; PMCID: PMC5502870

  88. Brown AS, Patel CJ. MeSHDD: Literature-based drug-drug similarity for drug repositioning. J Am Med Inform Assoc. 2017 May 01; 24(3):614-618. PMID: 27678460; PMCID: PMC5391732

  89. Brown AS, Patel CJ. A standard database for drug repositioning. Sci Data. 2017 03 14; 4:170029. PMID: 28291243

  90. Buck Louis GM, Smarr MM, Patel CJ. The Exposome Research Paradigm: an Opportunity to Understand the Environmental Basis for Human Health and Disease. Curr Environ Health Rep. 2017 03; 4(1):89-98. PMID: 28194614; PMCID: PMC5363405

  91. Patel CJ, Manrai AK, Corona E, Kohane IS. Systematic correlation of environmental exposure and physiological and self-reported behaviour factors with leukocyte telomere length. Int J Epidemiol. 2017 02 01; 46(1):44-56. PMID: 27059547; PMCID: PMC5407176

  92. Patel CJ. Analytic Complexity and Challenges in Identifying Mixtures of Exposures Associated with Phenotypes in the Exposome Era. Curr Epidemiol Rep. 2017; 4(1):22-30. PMID: 28251040; PMCID: PMC5306298

  93. Karczewski KJ, Tatonetti NP, Manrai AK, Patel CJ, Titus Brown C, Ioannidis JPA. METHODS TO ENSURE THE REPRODUCIBILITY OF BIOMEDICAL RESEARCH. Pac Symp Biocomput. 2017; 22:117-119. PMID: 27896967; PMCID: PMC5984201

  94. Manrai AK, Cui Y, Bushel PR, Hall M, Karakitsios S, Mattingly CJ, Ritchie M, Schmitt C, Sarigiannis DA, Thomas DC, Wishart D, Balshaw DM, Patel CJ. Informatics and Data Analytics to Support Exposome-Based Discovery for Public Health. Annu Rev Public Health. 2017 Mar 20; 38:279-294. PMID: 28068484

  95. Wulaningsih W, Van Hemelrijck M, Tsilidis KK, Tzoulaki I, Patel C, Rohrmann S. Investigating nutrition and lifestyle factors as determinants of abdominal obesity: an environment-wide study. Int J Obes (Lond). 2017 02; 41(2):340-347. PMID: 27840415

  96. Patel CJ, Sundaram R, Buck Louis GM. A data-driven search for semen-related phenotypes in conception delay. Andrology. 2017 01; 5(1):95-102. PMID: 27792860; PMCID: PMC5164952

  97. Patel CJ, Pho N, McDuffie M, Easton-Marks J, Kothari C, Kohane IS, Avillach P. A database of human exposomes and phenomes from the US National Health and Nutrition Examination Survey. Sci Data. 2016 10 25; 3:160096. PMID: 27779619

  98. Leppert J, Patel C. Perspective: Beyond the genome. Nature. 2016 09 15; 537(7620):S105. PMID: 27626778

  99. Patel CJ, Ji J, Sundquist J, Ioannidis JP, Sundquist K. Systematic assessment of pharmaceutical prescriptions in association with cancer risk: a method to conduct a population-wide medication-wide longitudinal study. Sci Rep. 2016 08 10; 6:31308. PMID: 27507038

  100. McGinnis DP, Brownstein JS, Patel CJ. Environment-Wide Association Study of Blood Pressure in the National Health and Nutrition Examination Survey (1999-2012). Sci Rep. 2016 07 26; 6:30373. PMID: 27457472

  101. Gao C, Patel CJ, Michailidou K, Peters U, Gong J, Schildkraut J, Schumacher FR, Zheng W, Boffetta P, Stucker I, Willett W, Gruber S, Easton DF, Hunter DJ, Sellers TA, Haiman C, Henderson BE, Hung RJ, Amos C, Pierce BL, Lindström S, Kraft P. Mendelian randomization study of adiposity-related traits and risk of breast, ovarian, prostate, lung and colorectal cancer. Int J Epidemiol. 2016 06; 45(3):896-908. PMID: 27427428; PMCID: PMC6372135

  102. Glicksberg BS, Li L, Badgeley MA, Shameer K, Kosoy R, Beckmann ND, Pho N, Hakenberg J, Ma M, Ayers KL, Hoffman GE, Dan Li S, Schadt EE, Patel CJ, Chen R, Dudley JT. Comparative analyses of population-scale phenomic data in electronic medical records reveal race-specific disease networks. Bioinformatics. 2016 06 15; 32(12):i101-i110. PMID: 27307606; PMCID: PMC4908366

  103. Patel CJ, Dominici F. Comment: Addressing the Need for Portability in Big Data Model Building and Calibration. J Am Stat Assoc. 2016; 111(513):127-129. PMID: 27867238

  104. Cote I, Andersen ME, Ankley GT, Barone S, Birnbaum LS, Boekelheide K, Bois FY, Burgoon LD, Chiu WA, Crawford-Brown D, Crofton KM, DeVito M, Devlin RB, Edwards SW, Guyton KZ, Hattis D, Judson RS, Knight D, Krewski D, Lambert J, Maull EA, Mendrick D, Paoli GM, Patel CJ, Perkins EJ, Poje G, Portier CJ, Rusyn I, Schulte PA, Simeonov A, Smith MT, Thayer KA, Thomas RS, Thomas R, Tice RR, Vandenberg JJ, Villeneuve DL, Wesselkamper S, Whelan M, Whittaker C, White R, Xia M, Yauk C, Zeise L, Zhao J, DeWoskin RS. The Next Generation of Risk Assessment Multi-Year Study-Highlights of Findings, Applications to Risk Assessment, and Future Directions. Environ Health Perspect. 2016 Nov; 124(11):1671-1682. PMID: 27091369; PMCID: PMC5089888

  105. Patel CJ. Analytical Complexity in Detection of Gene Variant-by-Environment Exposure Interactions in High-Throughput Genomic and Exposomic Research. Curr Environ Health Rep. 2016 Mar; 3(1):64-72. PMID: 26809563; PMCID: PMC4789192

  106. Brown AS, Kong SW, Kohane IS, Patel CJ. ksRepo: a generalized platform for computational drug repositioning. BMC Bioinformatics. 2016 Feb 09; 17:78. PMID: 26860211; PMCID: PMC4746802

  107. Manrai AK, Patel CJ, Gehlenborg N, Tatonetti NP, Ioannidis JP, Kohane IS. METHODS TO ENHANCE THE REPRODUCIBILITY OF PRECISION MEDICINE. Pac Symp Biocomput. 2016; 21:180-182. PMID: 28004011

  108. Manrai AK, Wang BL, Patel CJ, Kohane IS. REPRODUCIBLE AND SHAREABLE QUANTIFICATIONS OF PATHOGENICITY. Pac Symp Biocomput. 2016; 21:231-42. PMID: 26776189

  109. Merritt MA, Tzoulaki I, van den Brandt PA, Schouten LJ, Tsilidis KK, Weiderpass E, Patel CJ, Tjønneland A, Hansen L, Overvad K, His M, Dartois L, Boutron-Ruault MC, Fortner RT, Kaaks R, Aleksandrova K, Boeing H, Trichopoulou A, Lagiou P, Bamia C, Palli D, Krogh V, Tumino R, Ricceri F, Mattiello A, Bueno-de-Mesquita HB, Onland-Moret NC, Peeters PH, Skeie G, Jareid M, Quirós JR, Obón-Santacana M, Sánchez MJ, Chamosa S, Huerta JM, Barricarte A, Dias JA, Sonestedt E, Idahl A, Lundin E, Wareham NJ, Khaw KT, Travis RC, Ferrari P, Riboli E, Gunter MJ. Nutrient-wide association study of 57 foods/nutrients and epithelial ovarian cancer in the European Prospective Investigation into Cancer and Nutrition study and the Netherlands Cohort Study. Am J Clin Nutr. 2016 Jan; 103(1):161-7. PMID: 26607939; PMCID: PMC6459057

  110. Serghiou S, Patel CJ, Tan YY, Koay P, Ioannidis JP. Field-wide meta-analyses of observational associations can map selective availability of risk factors and the impact of model specifications. J Clin Epidemiol. 2016 Mar; 71:58-67. PMID: 26415577

  111. Brown AS, Patel CJ. aRrayLasso: a network-based approach to microarray interconversion. Bioinformatics. 2015 Dec 01; 31(23):3859-61. PMID: 26283699

  112. Patel CJ, Burford B, Ioannidis JP. Assessment of vibration of effects due to model specification can demonstrate the instability of observational associations. J Clin Epidemiol. 2015 Sep; 68(9):1046-58. PMID: 26279400

  113. Merritt MA, Tzoulaki I, Tworoger SS, De Vivo I, Hankinson SE, Fernandes J, Tsilidis KK, Weiderpass E, Tjønneland A, Petersen KE, Dahm CC, Overvad K, Dossus L, Boutron-Ruault MC, Fagherazzi G, Fortner RT, Kaaks R, Aleksandrova K, Boeing H, Trichopoulou A, Bamia C, Trichopoulos D, Palli D, Grioni S, Tumino R, Sacerdote C, Mattiello A, Bueno-de-Mesquita HB, Onland-Moret NC, Peeters PH, Gram IT, Skeie G, Quirós JR, Duell EJ, Sánchez MJ, Salmerón D, Barricarte A, Chamosa S, Ericson U, Sonestedt E, Nilsson LM, Idahl A, Khaw KT, Wareham N, Travis RC, Rinaldi S, Romieu I, Patel CJ, Riboli E, Gunter MJ. Investigation of dietary factors and endometrial cancer risk using a nutrient-wide association study approach in the EPIC and Nurses’ Health Study (NHS) and NHSII. Cancer Epidemiol Biomarkers Prev. 2015 Feb; 24(2):466-71. PMID: 25662427

  114. Patel CJ, Ioannidis JP, Cullen MR, Rehkopf DH. Systematic assessment of the correlations of household income with infectious, biochemical, physiological, and environmental factors in the United States, 1999-2006. Am J Epidemiol. 2015 Feb 01; 181(3):171-9. PMID: 25589242; PMCID: PMC4312426

  115. Patel CJ, Manrai AK. Development of exposome correlation globes to map out environment-wide associations. Pac Symp Biocomput. 2015; 231-42. PMID: 25592584; PMCID: PMC4299925

  116. Patel CJ, Ioannidis JP. Placing epidemiological results in the context of multiplicity and typical correlations of exposures. J Epidemiol Community Health. 2014 Nov; 68(11):1096-100. PMID: 24923805

  117. Patel CJ, Ioannidis JP. Studying the elusive environment in large scale. JAMA. 2014 Jun 04; 311(21):2173-4. PMID: 24893084; PMCID: PMC4110965

  118. Li L, Ruau DJ, Patel CJ, Weber SC, Chen R, Tatonetti NP, Dudley JT, Butte AJ. Disease risk factors identified through shared genetic architecture and electronic medical records. Sci Transl Med. 2014 Apr 30; 6(234):234ra57. PMID: 24786325

  119. Goodman M, LaKind JS, Fagliano JA, Lash TL, Wiemels JL, Winn DM, Patel C, Van Eenwyk J, Kohler BA, Schisterman EF, Albert P, Mattison DR. Cancer cluster investigations: review of the past and proposals for the future. Int J Environ Res Public Health. 2014 Jan 28; 11(2):1479-99. PMID: 24477211

  120. Patel CJ, Yang T, Hu Z, Wen Q, Sung J, El-Sayed YY, Cohen H, Gould J, Stevenson DK, Shaw GM, Ling XB, Butte AJ. Investigation of maternal environmental exposures in association with self-reported preterm birth. Reprod Toxicol. 2014 Jun; 45:1-7. PMID: 24373932

  121. Patel CJ, Rehkopf DH, Leppert JT, Bortz WM, Cullen MR, Chertow GM, Ioannidis JP. Systematic evaluation of environmental and behavioural factors associated with all-cause mortality in the United States national health and nutrition examination survey. Int J Epidemiol. 2013 Dec; 42(6):1795-810. PMID: 24345851; PMCID: PMC3887569

  122. Lankester J, Patel C, Cullen MR, Ley C, Parsonnet J. Urinary triclosan is associated with elevated body mass index in NHANES. PLoS One. 2013; 8(11):e80057. PMID: 24278238

  123. Weinberg AE, Eisenberg M, Patel CJ, Chertow GM, Leppert JT. Diabetes severity, metabolic syndrome, and the risk of erectile dysfunction. J Sex Med. 2013 Dec; 10(12):3102-9. PMID: 24010555; PMCID: PMC3891923

  124. Patel CJ, Sivadas A, Tabassum R, Preeprem T, Zhao J, Arafat D, Chen R, Morgan AA, Martin GS, Brigham KL, Butte AJ, Gibson G. Whole genome sequencing in support of wellness and health maintenance. Genome Med. 2013; 5(6):58. PMID: 23806097; PMCID: PMC3967117

  125. Kodama K, Tojjar D, Yamada S, Toda K, Patel CJ, Butte AJ. Ethnic differences in the relationship between insulin sensitivity and insulin response: a systematic review and meta-analysis. Diabetes Care. 2013 Jun; 36(6):1789-96. PMID: 23704681; PMCID: PMC3661854

  126. Corona E, Chen R, Sikora M, Morgan AA, Patel CJ, Ramesh A, Bustamante CD, Butte AJ. Analysis of the genetic basis of disease in the context of worldwide human relationships and migration. PLoS Genet. 2013 May; 9(5):e1003447. PMID: 23717210; PMCID: PMC3662561

  127. Patel CJ, Chen R, Kodama K, Ioannidis JP, Butte AJ. Systematic identification of interaction effects between validated genome- and environment-wide associations on Type 2 Diabetes Mellitus. AMIA Jt Summits Transl Sci Proc. 2013; 2013:135. PMID: 24303322

  128. Weinberg AE, Patel CJ, Chertow GM, Leppert JT. Diabetic severity and risk of kidney stone disease. Eur Urol. 2014 Jan; 65(1):242-7. PMID: 23523538

  129. Patel CJ, Chen R, Kodama K, Ioannidis JP, Butte AJ. Systematic identification of interaction effects between genome- and environment-wide associations in type 2 diabetes mellitus. Hum Genet. 2013 May; 132(5):495-508. PMID: 23334806

  130. Tzoulaki I, Patel CJ, Okamura T, Chan Q, Brown IJ, Miura K, Ueshima H, Zhao L, Van Horn L, Daviglus ML, Stamler J, Butte AJ, Ioannidis JP, Elliott P. A nutrient-wide association study on blood pressure. Circulation. 2012 Nov 20; 126(21):2456-64. PMID: 23093587; PMCID: PMC4105584

  131. Patel CJ, Chen R, Butte AJ. Data-driven integration of epidemiological and toxicological data to select candidate interacting genes and environmental factors in association with disease. Bioinformatics. 2012 Jun 15; 28(12):i121-6. PMID: 22689751

  132. Patel CJ, Cullen MR, Ioannidis JP, Butte AJ. Systematic evaluation of environmental factors: persistent pollutants and nutrients correlated with serum lipid levels. Int J Epidemiol. 2012 Jun; 41(3):828-43. PMID: 22421054; PMCID: PMC3396318

  133. Patel CJ, Cullen MR. Genetic variability in molecular responses to chemical exposure. Exp Suppl. 2012; 101:437-57. PMID: 22945578

  134. Patel CJ, Bhattacharya J, Butte AJ. An Environment-Wide Association Study (EWAS) on type 2 diabetes mellitus. PLoS One. 2010 May 20; 5(5):e10746. PMID: 20505766; PMCID: PMC2873978

  135. Patel CJ, Butte AJ. Predicting environmental chemical factors associated with disease-related gene expression data. BMC Med Genomics. 2010 May 06; 3:17. PMID: 20459635; PMCID: PMC2880288

  136. Zimmerman NH, Zimmerman N, Patel C, Chen DP, Chen DP. ChMP: A collaborative medical history portal. AMIA Annu Symp Proc. 2008 Nov 06; 859-63. PMID: 18999202